Kinetic and structure–activity studies of the triazolium ion-catalysed benzoin condensation
نویسندگان
چکیده
An initial rate evaluation of the triazolium-catalysed benzoin condensation permitted a Hammett structure–activity analysis providing insight into rate-limiting step.
منابع مشابه
The enantioselective benzoin condensation promoted by chiral triazolium precatalysts: stereochemical control via hydrogen bonding.
The design of a new class of triazolium ion precatalysts incorporating protic substituents is described. These materials promote the enantioselective benzoin condensation of a range of aromatic aldehydes (1-62% ee). Catalyst evaluation studies strongly support the involvement of hydrogen bond donation by the catalyst in the stereocentre-forming step of the catalytic cycle.
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ژورنال
عنوان ژورنال: Organic and Biomolecular Chemistry
سال: 2021
ISSN: ['1477-0520', '1477-0539']
DOI: https://doi.org/10.1039/d0ob02207a